Is DEF a valid Scrabble word?

Yes. DEF is valid in Collins Scrabble Words 2024, the word list used for Scrabble in the UK.

What DEF means

Definitions come from Wiktionary via kaikki.org, shortened to fit, and are used under CC BY-SA 4.0.

Anagrams of DEF

Gramlet is a daily word game played with the same Collins list. Play today's board.